Type 2 Diabetes and Glycemic Traits Are Not Causal Factors of Osteoarthritis: A Two-Sample Mendelian Randomization Analysis

BACKGROUND: It remains unclear whether an increased risk of type 2 diabetes (T2D) affects the risk of osteoarthritis (OA). METHODS: Here, we used two-sample Mendelian randomization (MR) to obtain non-confounded estimates of the effect of T2D and glycemic traits on hip and knee OA. We identified sing...

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Detaylı Bibliyografya
Yayımlandı:Front Genet
Asıl Yazarlar: Cui, Zhiyong, Feng, Hui, He, Baichuan, Xing, Yong, Liu, Zhaorui, Tian, Yun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2021
Konular:
Genetics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7838644/
https://ncbi.nlm.nih.gov/pubmed/33519901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.597876
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