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Tumor Mutational Burden (TMB) as a Predictive Biomarker in Solid Tumors
TMB, defined as the number of somatic mutations per megabase of interrogated genomic sequence, varies across malignancies. Panel sequencing-based estimates of TMB have largely replaced whole exome sequencing-derived TMB in the clinic. Retrospective evidence suggests that TMB can predict the efficacy...
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| Publicado no: | Cancer Discov |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7710563/ https://ncbi.nlm.nih.gov/pubmed/33139244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-20-0522 |
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