Disease modeling and stem cell immunoengineering in regenerative medicine using CRISPR/Cas9 systems

CRISPR/Cas systems are popular genome editing tools that belong to a class of programmable nucleases and have enabled tremendous progress in the field of regenerative medicine. We here outline the structural and molecular frameworks of the well-characterized type II CRISPR system and several computa...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Antao, Ainsley Mike, Karapurkar, Janardhan Keshav, Lee, Dong Ryul, Kim, Kye-Seong, Ramakrishna, Suresh
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710510/
https://ncbi.nlm.nih.gov/pubmed/33304462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.11.026
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