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Advances in Deubiquitinating Enzyme Inhibition and Applications in Cancer Therapeutics
Since the discovery of the ubiquitin proteasome system (UPS), the roles of ubiquitinating and deubiquitinating enzymes (DUBs) have been widely elucidated. The ubiquitination of proteins regulates many aspects of cellular functions such as protein degradation and localization, and also modifies prote...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7352412/ https://ncbi.nlm.nih.gov/pubmed/32549302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061579 |
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