Critical Roles of Deubiquitinating Enzymes in the Nervous System and Neurodegenerative Disorders

Post-translational modifications play major roles in the stability, function, and localization of target proteins involved in the nervous system. The ubiquitin-proteasome pathway uses small ubiquitin molecules to degrade neuronal proteins. Deubiquitinating enzymes (DUBs) reverse this degradation and...

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Published in:Mol Cells
Main Authors: Das, Soumyadip, Ramakrishna, Suresh, Kim, Kye-Seong
Format: Artigo
Language:Inglês
Published: Korean Society for Molecular and Cellular Biology 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103888/
https://ncbi.nlm.nih.gov/pubmed/32133826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2020.2289
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