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Expanding the Chemogenetic Toolbox by Circular Permutation

To expand the repertoire of chemogenetic tools tailored for molecular and cellular engineering, we describe herein the design of cpRAPID as a circularly permuted rapamycin-inducible dimerization system composed of the canonical FK506-binding protein (FKBP) and circular permutants of FKBP12–rapamycin...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Lee, Yi-Tsang, He, Lian, Zhou, Yubin
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710497/
https://ncbi.nlm.nih.gov/pubmed/32277990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.03.033
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