Dexmedetomidine Protects against Myocardial Ischemia/Reperfusion Injury by Ameliorating Oxidative Stress and Cell Apoptosis through the Trx1-Dependent Akt Pathway

Dexmedetomidine (Dex) was reported to reduce oxidative stress and protect against myocardial Ischemia/Reperfusion (I/R) injury. However, the molecular mechanism involved in its antioxidant property is not fully elucidated. The present study was aimed at investigating whether the Trx1/Akt pathway par...

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Bibliografiske detaljer
Udgivet i:Biomed Res Int
Main Authors: Wu, Zhi-lin, Davis, Jacques Robert Jeppe, Zhu, Yi
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710428/
https://ncbi.nlm.nih.gov/pubmed/33299886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8979270
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