Dexmedetomidine Protects against Myocardial Ischemia/Reperfusion Injury by Ameliorating Oxidative Stress and Cell Apoptosis through the Trx1-Dependent Akt Pathway

Dexmedetomidine (Dex) was reported to reduce oxidative stress and protect against myocardial Ischemia/Reperfusion (I/R) injury. However, the molecular mechanism involved in its antioxidant property is not fully elucidated. The present study was aimed at investigating whether the Trx1/Akt pathway par...

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Publicado en:Biomed Res Int
Autores principales: Wu, Zhi-lin, Davis, Jacques Robert Jeppe, Zhu, Yi
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710428/
https://ncbi.nlm.nih.gov/pubmed/33299886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8979270
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