Early disruption of nerve mitochondrial and myelin lipid homeostasis in obesity-induced diabetes

Diabetic neuropathy is a major complication of diabetes. Current treatment options alleviate pain but do not stop the progression of the disease. At present, there are no approved disease-modifying therapies. Thus, developing more effective therapies remains a major unmet medical need. Seeking to be...

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Vydáno v:JCI Insight
Hlavní autoři: Palavicini, Juan P., Chen, Juan, Wang, Chunyan, Wang, Jianing, Qin, Chao, Baeuerle, Eric, Wang, Xinming, Woo, Jung A., Kang, David E., Musi, Nicolas, Dupree, Jeffrey L., Han, Xianlin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710310/
https://ncbi.nlm.nih.gov/pubmed/33148881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.137286
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