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CFTR Deletion Confers Mitochondrial Dysfunction and Disrupts Lipid Homeostasis in Intestinal Epithelial Cells

Background: Cystic Fibrosis (CF) is a genetic disease in which the intestine exhibits oxidative and inflammatory markers. As mitochondria are the central source and the main target of reactive oxygen species, we hypothesized that cystic fibrosis transmembrane conductance regulator (CFTR) defect lead...

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Detalhes bibliográficos
Publicado no:Nutrients
Main Authors: Kleme, Marie L., Sané, Alain, Garofalo, Carole, Seidman, Ernest, Brochiero, Emmanuelle, Berthiaume, Yves, Levy, Emile
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6073936/
https://ncbi.nlm.nih.gov/pubmed/29954133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu10070836
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