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CFTR Deletion Confers Mitochondrial Dysfunction and Disrupts Lipid Homeostasis in Intestinal Epithelial Cells

Background: Cystic Fibrosis (CF) is a genetic disease in which the intestine exhibits oxidative and inflammatory markers. As mitochondria are the central source and the main target of reactive oxygen species, we hypothesized that cystic fibrosis transmembrane conductance regulator (CFTR) defect lead...

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Publicado en:Nutrients
Autores principales: Kleme, Marie L., Sané, Alain, Garofalo, Carole, Seidman, Ernest, Brochiero, Emmanuelle, Berthiaume, Yves, Levy, Emile
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6073936/
https://ncbi.nlm.nih.gov/pubmed/29954133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu10070836
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