IgG3 collaborates with IgG1 and IgA to recruit effector function in RV144 vaccinees

While the RV144 HIV vaccine trial led to moderately reduced risk of HIV acquisition, emerging data from the HVTN702 trial point to the critical need to reexamine RV144-based correlates of reduced risk of protection. While in RV144, the induction of V2-binding, non-IgA, IgG3 antibody responses with n...

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Dettagli Bibliografici
Pubblicato in:JCI Insight
Autori principali: Fischinger, Stephanie, Dolatshahi, Sepideh, Jennewein, Madeleine F., Rerks-Ngarm, Supachai, Pitisuttithum, Punnee, Nitayaphan, Sorachai, Michael, Nelson, Vasan, Sandhya, Ackerman, Margaret E., Streeck, Hendrik, Alter, Galit
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710302/
https://ncbi.nlm.nih.gov/pubmed/33031099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140925
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