Machine Learning Methods Enable Predictive Modeling of Antibody Feature:Function Relationships in RV144 Vaccinees

The adaptive immune response to vaccination or infection can lead to the production of specific antibodies to neutralize the pathogen or recruit innate immune effector cells for help. The non-neutralizing role of antibodies in stimulating effector cell responses may have been a key mechanism of the...

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Publicado no:PLoS Comput Biol
Main Authors: Choi, Ickwon, Chung, Amy W., Suscovich, Todd J., Rerks-Ngarm, Supachai, Pitisuttithum, Punnee, Nitayaphan, Sorachai, Kaewkungwal, Jaranit, O'Connell, Robert J., Francis, Donald, Robb, Merlin L., Michael, Nelson L., Kim, Jerome H., Alter, Galit, Ackerman, Margaret E., Bailey-Kellogg, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395155/
https://ncbi.nlm.nih.gov/pubmed/25874406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004185
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