Machine Learning Methods Enable Predictive Modeling of Antibody Feature:Function Relationships in RV144 Vaccinees

The adaptive immune response to vaccination or infection can lead to the production of specific antibodies to neutralize the pathogen or recruit innate immune effector cells for help. The non-neutralizing role of antibodies in stimulating effector cell responses may have been a key mechanism of the...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Choi, Ickwon, Chung, Amy W., Suscovich, Todd J., Rerks-Ngarm, Supachai, Pitisuttithum, Punnee, Nitayaphan, Sorachai, Kaewkungwal, Jaranit, O'Connell, Robert J., Francis, Donald, Robb, Merlin L., Michael, Nelson L., Kim, Jerome H., Alter, Galit, Ackerman, Margaret E., Bailey-Kellogg, Chris
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395155/
https://ncbi.nlm.nih.gov/pubmed/25874406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004185
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