Utilization of Whole Exome Sequencing Data to Identify Clinically Relevant Pharmacogenomic Variants in Pediatric Inflammatory Bowel Disease

INTRODUCTION: We hypothesized that variants within clinically relevant pharmacogenes could be identified using a whole exome sequencing data set derived from a cohort of more than 1,000 patients with inflammatory bowel disease (IBD). METHODS: Pediatric patients diagnosed with IBD underwent whole exo...

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Detalhes bibliográficos
Publicado no:Clin Transl Gastroenterol
Main Authors: Mulder, Daniel J., Khalouei, Sam, Warner, Neil, Gonzaga-Jauregui, Claudia, Church, Peter C., Walters, Thomas D., Ramani, Arun K., Griffiths, Anne M., Cohn, Iris, Muise, Aleixo M.
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710220/
https://ncbi.nlm.nih.gov/pubmed/33512800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14309/ctg.0000000000000263
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