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Molecular role of cytochrome P4501A enzymes inoxidative stress

Cytochrome P4501A (CYP1A) enzymes play important roles in xenobiotic and endobiotic metabolism. Due to uncoupling reactions during the enzymatic cycle, CYP1A enzymes can release reactive oxidative species (ROS) in the form of superoxide radical, hydrogen peroxide, hydroxyl radical etc. An imbalance...

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Bibliografiska uppgifter
I publikationen:Curr Opin Toxicol
Huvudupphovsmän: Stading, Rachel, Chu, Chun, Couroucli, Xanthi, Lingappan, Krithika, Moorthy, Bhagavatula
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7709944/
https://ncbi.nlm.nih.gov/pubmed/33283080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cotox.2020.07.001
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