Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway

Diastolic dysfunction is condition of a stiff ventricle and a function of aging. It causes significant cardiovascular mortality and morbidity, and in fact, three million Americans are currently suffering from this condition. To date, all the pharmacological clinical trials have been negative. The la...

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Detalhes bibliográficos
Publicado no:Front Cardiovasc Med
Main Authors: Moudgil, Rohit, Samra, Gursharan, Ko, Kyung Ae, Vu, Hang Thi, Thomas, Tamlyn N., Luo, Weijia, Chang, Jiang, Reddy, Anilkumar K., Fujiwara, Keigi, Abe, Jun-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cardiovascular Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7709875/
https://ncbi.nlm.nih.gov/pubmed/33330654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2020.594123
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