Gestational arsenic exposure induces site-specific DNA hypomethylation in active retrotransposon subfamilies in offspring sperm in mice

BACKGROUND: Environmental impacts on a fetus can disrupt germ cell development leading to epimutations in mature germ cells. Paternal inheritance of adverse health effects through sperm epigenomes, including DNA methylomes, has been recognized in human and animal studies. However, the impacts of ges...

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Vydáno v:Epigenetics Chromatin
Hlavní autoři: Nohara, Keiko, Nakabayashi, Kazuhiko, Okamura, Kazuyuki, Suzuki, Takehiro, Suzuki, Shigekatsu, Hata, Kenichiro
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7709384/
https://ncbi.nlm.nih.gov/pubmed/33267854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-020-00375-3
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