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Complement Activation in the Treatment of B-Cell Malignancies

Unconjugated monoclonal antibodies (mAb) have revolutionized the treatment of B-cell malignancies. These targeted drugs can activate innate immune cytotoxicity for therapeutic benefit. mAb activation of the complement cascade results in complement-dependent cytotoxicity (CDC) and complement receptor...

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Dades bibliogràfiques
Publicat a:Antibodies (Basel)
Autors principals: Zent, Clive S., Pinney, Jonathan J., Chu, Charles C., Elliott, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7709106/
https://ncbi.nlm.nih.gov/pubmed/33271825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib9040068
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