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Bi-allelic Pro291Leu variant in KCNQ4 leads to early onset non-syndromic hearing loss

Variants of KCNQ4 are one of the most common causes of dominantly inherited nonsyndromic hearing loss. We investigated a consanguineous family in which two individuals had prelignual hearing loss, apparently inherited in a recessive mode. Whole-exome sequencing analyses demonstrated genetic heteroge...

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Bibliografiske detaljer
Udgivet i:Gene
Main Authors: Ramzan, Memoona, Idrees, Hafiza, Mujtaba, Ghulam, Sobreira, Nara, Witmer, P. Dane, Naz, Sadaf
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7709079/
https://ncbi.nlm.nih.gov/pubmed/31028865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2019.04.064
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