Functionally impaired plasmacytoid dendritic cells and non-haematopoietic sources of type I interferon characterize human autoimmunity

Autoimmune connective tissue diseases arise in a stepwise fashion from asymptomatic preclinical autoimmunity. Type I interferons have a crucial role in the progression to established autoimmune diseases. The cellular source and regulation in disease initiation of these cytokines is not clear, but pl...

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Publicado no:Nat Commun
Main Authors: Psarras, Antonios, Alase, Adewonuola, Antanaviciute, Agne, Carr, Ian M., Md Yusof, Md Yuzaiful, Wittmann, Miriam, Emery, Paul, Tsokos, George C., Vital, Edward M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708979/
https://ncbi.nlm.nih.gov/pubmed/33262343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19918-z
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