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Unexpected diversity of CRISPR unveils some evolutionary patterns of repeated sequences in Mycobacterium tuberculosis

BACKGROUND: Diversity of the CRISPR locus of Mycobacterium tuberculosis complex has been studied since 1997 for molecular epidemiology purposes. By targeting solely the 43 spacers present in the two first sequenced genomes (H37Rv and BCG), it gave a biased idea of CRISPR diversity and ignored divers...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Refrégier, Guislaine, Sola, Christophe, Guyeux, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708916/
https://ncbi.nlm.nih.gov/pubmed/33256602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-07178-6
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