Effects of Saikosaponin D on CYP1A2 and CYP2D6 in HepaRG Cells

BACKGROUND: Bupleurum is one of the most important traditional Chinese medicines and an ingredient in many compound preparations. It is widely used together with other drugs in clinical practice, and thus there is great potential for drug–drug interactions. Saikosaponin D (SsD) is a major bioactive...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Drug Des Devel Ther
Main Authors: Li, Hongfang, Tang, Yunyan, Wang, Yang, Wei, Weipeng, Yin, Chengchen, Tang, Fushang
Format: Artigo
Jezik:Inglês
Izdano: Dove 2020
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708782/
https://ncbi.nlm.nih.gov/pubmed/33273809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S268358
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