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AMPA RECEPTOR CONTRIBUTION TO METHYLMERCURY-MEDIATED ALTERATION OF INTRACELLULAR Ca(2+) CONCENTRATION IN HUMAN INDUCED PLURIPOTENT STEM CELL MOTOR NEURONS
α motor neurons (MNs) are a target of the environmental neurotoxicant methylmercury (MeHg), accumulating MeHg and subsequently degenerating. In mouse spinal cord MN cultures, MeHg increased intracellular Ca(2+) [Ca(2+)](i); the AMPA receptor (AMPAR) antagonist CNQX delayed the increase in [Ca(2+)](i...
Gardado en:
| Publicado en: | Neurotoxicology |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7708444/ https://ncbi.nlm.nih.gov/pubmed/32991939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2020.09.037 |
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