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AMPA RECEPTOR CONTRIBUTION TO METHYLMERCURY-MEDIATED ALTERATION OF INTRACELLULAR Ca(2+) CONCENTRATION IN HUMAN INDUCED PLURIPOTENT STEM CELL MOTOR NEURONS

α motor neurons (MNs) are a target of the environmental neurotoxicant methylmercury (MeHg), accumulating MeHg and subsequently degenerating. In mouse spinal cord MN cultures, MeHg increased intracellular Ca(2+) [Ca(2+)](i); the AMPA receptor (AMPAR) antagonist CNQX delayed the increase in [Ca(2+)](i...

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Detaylı Bibliyografya
Yayımlandı:Neurotoxicology
Asıl Yazarlar: Colón-Rodríguez, Alexandra, Colón-Carrión, Nicole M., Atchison, William D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708444/
https://ncbi.nlm.nih.gov/pubmed/32991939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2020.09.037
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