Wird geladen...

The ssDNA-binding protein MEIOB acts as a dosage-sensitive regulator of meiotic recombination

Meiotic recombination enables reciprocal exchange of genetic information between parental chromosomes and is essential for fertility. MEIOB, a meiosis-specific ssDNA-binding protein, regulates early meiotic recombination. Here we report that the human infertility-associated missense mutation (N64I)...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Guo, Rui, Xu, Yang, Leu, N Adrian, Zhang, Lei, Fuchs, Serge Y, Ye, Lan, Wang, P Jeremy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708077/
https://ncbi.nlm.nih.gov/pubmed/33166385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1016
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!