Improved nearest-neighbor parameters for the stability of RNA/DNA hybrids under a physiological condition

The stability of Watson–Crick paired RNA/DNA hybrids is important for designing optimal oligonucleotides for ASO (Antisense Oligonucleotide) and CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)–Cas9 techniques. Previous nearest-neighbour (NN) parameters for predicting hybrid stabil...

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發表在:Nucleic Acids Res
Main Authors: Banerjee, Dipanwita, Tateishi-Karimata, Hisae, Ohyama, Tatsuya, Ghosh, Saptarshi, Endoh, Tamaki, Takahashi, Shuntaro, Sugimoto, Naoki
格式: Artigo
語言:Inglês
出版: Oxford University Press 2020
主題:
Data Resources and Analyses
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708073/
https://ncbi.nlm.nih.gov/pubmed/32663294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa572
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