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Improved nearest-neighbor parameters for the stability of RNA/DNA hybrids under a physiological condition
The stability of Watson–Crick paired RNA/DNA hybrids is important for designing optimal oligonucleotides for ASO (Antisense Oligonucleotide) and CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)–Cas9 techniques. Previous nearest-neighbour (NN) parameters for predicting hybrid stabil...
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| 發表在: | Nucleic Acids Res |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7708073/ https://ncbi.nlm.nih.gov/pubmed/32663294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa572 |
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