Nearest-neighbor parameters for predicting DNA duplex stability in diverse molecular crowding conditions

The intracellular environment is crowded and heterogeneous. Although the thermodynamic stability of nucleic acid duplexes is predictable in dilute solutions, methods of predicting such stability under specific intracellular conditions are not yet available. We recently showed that the nearest-neighb...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Ghosh, Saptarshi, Takahashi, Shuntaro, Ohyama, Tatsuya, Endoh, Tamaki, Tateishi-Karimata, Hisae, Sugimoto, Naoki
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2020
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321957/
https://ncbi.nlm.nih.gov/pubmed/32522884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1920886117
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