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Nearest-neighbor parameters for predicting DNA duplex stability in diverse molecular crowding conditions
The intracellular environment is crowded and heterogeneous. Although the thermodynamic stability of nucleic acid duplexes is predictable in dilute solutions, methods of predicting such stability under specific intracellular conditions are not yet available. We recently showed that the nearest-neighb...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7321957/ https://ncbi.nlm.nih.gov/pubmed/32522884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1920886117 |
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