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Nearest-neighbor parameters for predicting DNA duplex stability in diverse molecular crowding conditions

The intracellular environment is crowded and heterogeneous. Although the thermodynamic stability of nucleic acid duplexes is predictable in dilute solutions, methods of predicting such stability under specific intracellular conditions are not yet available. We recently showed that the nearest-neighb...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Ghosh, Saptarshi, Takahashi, Shuntaro, Ohyama, Tatsuya, Endoh, Tamaki, Tateishi-Karimata, Hisae, Sugimoto, Naoki
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321957/
https://ncbi.nlm.nih.gov/pubmed/32522884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1920886117
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