PpCas9 from Pasteurella pneumotropica — a compact Type II-C Cas9 ortholog active in human cells

CRISPR-Cas defense systems opened up the field of genome editing due to the ease with which effector Cas nucleases can be programmed with guide RNAs to access desirable genomic sites. Type II-A SpCas9 from Streptococcus pyogenes was the first Cas9 nuclease used for genome editing and it remains the...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Fedorova, Iana, Vasileva, Aleksandra, Selkova, Polina, Abramova, Marina, Arseniev, Anatolii, Pobegalov, Georgii, Kazalov, Maksim, Musharova, Olga, Goryanin, Ignatiy, Artamonova, Daria, Zyubko, Tatyana, Shmakov, Sergey, Artamonova, Tatyana, Khodorkovskii, Mikhail, Severinov, Konstantin
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Nucleic Acid Enzymes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708072/
https://ncbi.nlm.nih.gov/pubmed/33152077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa998
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