PpCas9 from Pasteurella pneumotropica — a compact Type II-C Cas9 ortholog active in human cells

CRISPR-Cas defense systems opened up the field of genome editing due to the ease with which effector Cas nucleases can be programmed with guide RNAs to access desirable genomic sites. Type II-A SpCas9 from Streptococcus pyogenes was the first Cas9 nuclease used for genome editing and it remains the...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Fedorova, Iana, Vasileva, Aleksandra, Selkova, Polina, Abramova, Marina, Arseniev, Anatolii, Pobegalov, Georgii, Kazalov, Maksim, Musharova, Olga, Goryanin, Ignatiy, Artamonova, Daria, Zyubko, Tatyana, Shmakov, Sergey, Artamonova, Tatyana, Khodorkovskii, Mikhail, Severinov, Konstantin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708072/
https://ncbi.nlm.nih.gov/pubmed/33152077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa998
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