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Histone sumoylation promotes Set3 histone-deacetylase complex-mediated transcriptional regulation

Histones are substrates of the SUMO (small ubiquitin-like modifier) conjugation pathway. Several reports suggest histone sumoylation affects transcription negatively, but paradoxically, our genome-wide analysis shows the modification concentrated at many active genes. We find that trans-tail regulat...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Ryu, Hong-Yeoul, Zhao, Dejian, Li, Jianhui, Su, Dan, Hochstrasser, Mark
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708062/
https://ncbi.nlm.nih.gov/pubmed/33231641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1093
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