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Requirements for efficient ligand-gated co-transcriptional switching in designed variants of the B. subtilis pbuE adenine-responsive riboswitch in E. coli

Riboswitches, generally located in the 5’-leader of bacterial mRNAs, direct expression via a small molecule-dependent structural switch that informs the transcriptional or translational machinery. While the structure and function of riboswitch effector-binding (aptamer) domains have been intensely s...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Drogalis, Lea K., Batey, Robert T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7707468/
https://ncbi.nlm.nih.gov/pubmed/33259551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0243155
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