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A six-amino-acid motif is a major determinant in functional evolution of HOX1 proteins

Gene duplication and divergence is a major driver in the emergence of evolutionary novelties. How variations in amino acid sequences lead to loss of ancestral activity and functional diversification of proteins is poorly understood. We used cross-species functional analysis of Drosophila Labial and...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Singh, Narendra Pratap, De Kumar, Bony, Paulson, Ariel, Parrish, Mark E., Zhang, Ying, Florens, Laurence, Conaway, Joan W., Si, Kausik, Krumlauf, Robb
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7706710/
https://ncbi.nlm.nih.gov/pubmed/33184220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.342329.120
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