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Chromosome-autonomous feedback down-regulates meiotic DNA break competence upon synaptonemal complex formation
The number of DNA double-strand breaks (DSBs) initiating meiotic recombination is elevated in Saccharomyces cerevisiae mutants that are globally defective in forming crossovers and synaptonemal complex (SC), a protein scaffold juxtaposing homologous chromosomes. These mutants thus appear to lack a n...
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| Publicado no: | Genes Dev |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7706706/ https://ncbi.nlm.nih.gov/pubmed/33184224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.342873.120 |
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