Dioxin Disrupts Dynamic DNA Methylation Patterns in Genes That Govern Cardiomyocyte Maturation

Congenital heart disease (CHD), the leading birth defect worldwide, has a largely unknown etiology, likely to result from complex interactions between genetic and environmental factors during heart development, at a time when the heart adapts to diverse physiological and pathophysiological condition...

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Bibliographische Detailangaben
Veröffentlicht in:Toxicol Sci
Hauptverfasser: de Gannes, Matthew, Ko, Chia-I, Zhang, Xiang, Biesiada, Jacek, Niu, Liang, Koch, Sheryl E, Medvedovic, Mario, Rubinstein, Jack, Puga, Alvaro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Genetic and Epigenetic Toxicology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7706406/
https://ncbi.nlm.nih.gov/pubmed/33017471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfaa153
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