Aryl Hydrocarbon Receptor Ablation in Cardiomyocytes Protects Male Mice From Heart Dysfunction Induced by NKX2.5 Haploinsufficiency

Epidemiological studies in humans and research in vertebrates indicates that developmental exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a ubiquitous and biopersistent environmental toxicant, is associated with incidence of early congenital heart disease in the embryo and later in the adul...

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Vydáno v:Toxicol Sci
Hlavní autoři: Wang, Qin, Fan, Yunxia, Kurita, Hisaka, Jiang, Min, Koch, Sheryl, Rao, Marepalli B., Rubinstein, Jack, Puga, Alvaro
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Aryl Hydrocarbon Receptor in Cardiac Differentiation and Dysfunction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837197/
https://ncbi.nlm.nih.gov/pubmed/28973413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx164
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