Negative control of diacylglycerol kinase ζ-mediated inhibition of T cell receptor signaling by nuclear sequestration in mice

Diacylglycerol kinases (DGKs) play important roles in restraining diacylglycerol (DAG)-mediated signaling. Within the DGK family, the ζ isoform appears to be the most important isoform in T cells for controlling their development and function. DGKζ has been demonstrated to regulate T cell maturation...

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Veröffentlicht in:Eur J Immunol
Hauptverfasser: Xie, Danli, Zhang, Shimeng, Cheng, Pengcheng, Deng, Wenhai, Pan, Yun, Xie, Jinhai, Wang, Jinli, Liao, Bryce, Sleasman, John W., Zhong, Xiao-Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705894/
https://ncbi.nlm.nih.gov/pubmed/32525220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201948442
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