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Efflux Pump AcrAB Confers Decreased Susceptibility to Piperacillin–Tazobactam and Ceftolozane–Tazobactam in Tigecycline-Non-Susceptible Klebsiella pneumoniae

INTRODUCTION: Drug efflux pumps are critical for resistance in Gram-negative organisms, but there are limited data on the role they play in decreased susceptibility to β-lactam/β-lactamase inhibitor combinations. In this study, we aimed to investigate the impact of efflux pump AcrAB on piperacillin–...

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Détails bibliographiques
Publié dans:Infect Drug Resist
Auteurs principaux: Li, Junjie, Xu, Qingqing, Ogurek, Sean, Li, Ziqiang, Wang, Peiyun, Xie, Qing, Sheng, Zike, Wang, Minggui
Format: Artigo
Langue:Inglês
Publié: Dove 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705282/
https://ncbi.nlm.nih.gov/pubmed/33273833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S279020
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