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Calcium Oscillations in Pancreatic α-cells Rely on Noise and ATP-Driven Changes in Membrane Electrical Activity

In pancreatic α-cells, intracellular Ca(2+) ([Ca(2+)](i)) acts as a trigger for secretion of glucagon, a hormone that plays a key role in blood glucose homeostasis. Intracellular Ca(2+) dynamics in these cells are governed by the electrical activity of voltage-gated ion channels, among which ATP-sen...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: González-Vélez, Virginia, Piron, Anthony, Dupont, Geneviève
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705205/
https://ncbi.nlm.nih.gov/pubmed/33281631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.602844
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