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Sphingolipids and Inositol Phosphates Regulate the Tau Protein Phosphorylation Status in Humanized Yeast

Hyperphosphorylation of protein tau is a hallmark of Alzheimer’s disease (AD). Changes in energy and lipid metabolism have been correlated with the late onset of this neurological disorder. However, it is uncertain if metabolic dysregulation is a consequence of AD or one of the initiating factors of...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Randez-Gil, Francisca, Bojunga, Lino, Estruch, Francisco, Winderickx, Joris, Del Poeta, Maurizio, Prieto, Jose A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705114/
https://ncbi.nlm.nih.gov/pubmed/33282871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.592159
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