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The Novel SOD Mimetic GC4419 Increases Cancer Cell Killing With Sensitization to Ionizing Radiation While Protecting Normal Cells

While radiotherapy is a widely used treatment for many types of human cancer, problems of radio-resistance and side effects remain. Side effects induced by ionizing radiation (IR) arise primarily from its propensity to trigger inflammation and oxidative stress with damage of normal cells and tissues...

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Publicat a:Free Radic Biol Med
Autors principals: El-Mahdy, Mohamed A., Alzarie, Yasmin A., Hemann, Craig, Badary, Osama A., Nofal, Shahira, Zweier, Jay L.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704930/
https://ncbi.nlm.nih.gov/pubmed/32739595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2020.07.032
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