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Trityl radicals in perfluorocarbon emulsions as stable, sensitive, and biocompatible oximetry probes

EPR oximetry with the use of trityl radicals can enable sensitive O(2) measurement in biological cells and tissues. However, in vitro cellular and in vivo biological applications are limited by rapid trityl probe degradation or biological clearance and the need to enhance probe O (2) sensitivity. We...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Dhimitruka, Ilirian, Alzarie, Yasmin Alsayed, Hemann, Craig, Samouilov, Alexandre, Zweier, Jay L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5141683/
https://ncbi.nlm.nih.gov/pubmed/27836400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.10.066
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