Signalosome-Regulated SRF Phosphorylation Determining Myocyte Growth in Width versus Length As a Therapeutic Target for Heart Failure

BACKGROUND: Concentric and eccentric cardiac hypertrophy are associated with pressure and volume overload, respectively, in cardiovascular disease both conferring an increased risk of heart failure. These contrasting forms of hypertrophy are characterized by asymmetric growth of the cardiac myocyte...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Li, Jinliang, Tan, Yuliang, Passariello, Catherine L., Martinez, Eliana C., Kritzer, Michael D., Li, Xueyi, Li, Xiaofeng, Li, Yang, Yu, Qian, Ohgi, Kenneth, Thakur, Hrishikesh, MacArthur, John W., Ivey, Jan R., Woo, Y. Joseph, Emter, Craig A., Dodge-Kafka, Kimberly, Rosenfeld, Michael G., Kapiloff, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704863/
https://ncbi.nlm.nih.gov/pubmed/32933333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.119.044805
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