Chronic activation of GPR40 does not negatively impact upon BRIN-BD11 pancreatic β-cell physiology and function

BACKGROUND: Free fatty acids (FFAs) are known for their dual effects on insulin secretion and pancreatic β-cell survival. Short-term exposure to FFAs, such as palmitate, increases insulin secretion. On the contrary, long-term exposure to saturated FFAs results in decreased insulin secretion, as well...

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Detalhes bibliográficos
Publicado no:Pharmacol Rep
Main Authors: Vilas-Boas, Eloisa Aparecida, Karabacz, Noémie, Marsiglio-Librais, Gabriela Nunes, Valle, Maíra Melo Rezende, Nalbach, Lisa, Ampofo, Emmanuel, Morgan, Bruce, Carpinelli, Angelo Rafael, Roma, Leticia Prates
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704488/
https://ncbi.nlm.nih.gov/pubmed/32274767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s43440-020-00101-6
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