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Changes in cAMP effector predominance are associated with increased oxytocin receptor expression in twin but not infection-associated or idiopathic preterm labour

We previously reported that at term pregnancy, a decline in myometrial protein kinase A (PKA) activity leads to an exchange protein activated by cyclic AMP (Epac1)-dependent increase in oxytocin receptor (OTR) expression, promoting the onset of labour. Here, we studied the changes in the cyclic aden...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yulia, Angela, Varley, Alice J., Singh, Natasha, Lei, Kaiyu, Tribe, Rachel, Johnson, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703985/
https://ncbi.nlm.nih.gov/pubmed/33253216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240325
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