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Clinical and Genetic Implications of DNA Mismatch Repair Deficiency in Biliary Tract Cancers Associated with Lynch Syndrome

PURPOSE: Patients with Lynch syndrome (LS) have a significantly elevated lifetime risk of developing biliary tract cancers (BTCs) compared to the general population. However, few studies have characterized the clinical characteristics, genetic features, or long-term outcomes of mismatch-repair defic...

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Publicat a:J Gastrointest Cancer
Autors principals: Cloyd, Jordan M, Chun, Yun Shin, Ikoma, Naruhiko, Vauthey, Jean Nicolas, Aloia, Tlhomas A., Cuddy, Amanda, Rodriguez-Bigas, Miguel A., You, Y. Nancy
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703856/
https://ncbi.nlm.nih.gov/pubmed/29238914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12029-017-0040-9
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