H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation

The discovery of H3K27M mutations in pediatric gliomas marked a new chapter in cancer epigenomics. Numerous studies have investigated the effect of this mutation on H3K27 trimethylation, but only recently have we started to realize its additional effects on the epigenome. Here, we use isogenic gliom...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Cell Rep
Главные авторы: Harutyunyan, Ashot S., Chen, Haifen, Lu, Tianyuan, Horth, Cynthia, Nikbakht, Hamid, Krug, Brian, Russo, Caterina, Bareke, Eric, Marchione, Dylan M., Coradin, Mariel, Garcia, Benjamin A., Jabado, Nada, Majewski, Jacek
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703850/
https://ncbi.nlm.nih.gov/pubmed/33207202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108390
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы