H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation

The discovery of H3K27M mutations in pediatric gliomas marked a new chapter in cancer epigenomics. Numerous studies have investigated the effect of this mutation on H3K27 trimethylation, but only recently have we started to realize its additional effects on the epigenome. Here, we use isogenic gliom...

詳細記述

保存先:
書誌詳細
出版年:Cell Rep
主要な著者: Harutyunyan, Ashot S., Chen, Haifen, Lu, Tianyuan, Horth, Cynthia, Nikbakht, Hamid, Krug, Brian, Russo, Caterina, Bareke, Eric, Marchione, Dylan M., Coradin, Mariel, Garcia, Benjamin A., Jabado, Nada, Majewski, Jacek
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703850/
https://ncbi.nlm.nih.gov/pubmed/33207202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108390
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