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CRISPR RNA-guided autonomous delivery of Cas9

Cas9 is an endonuclease that can be programed to autonomously deliver diverse effectors to specified genetic addresses. High-resolution structures of this protein and its associated CRISPR RNA (crRNA) guide explain the molecular mechanisms of crRNA-guided DNA recognition and provide a molecular blue...

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Bibliografiska uppgifter
I publikationen:Nat Struct Mol Biol
Huvudupphovsmän: Wilkinson, Royce A., Martin, Coleman, Wiedenheft, Blake
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703833/
https://ncbi.nlm.nih.gov/pubmed/30598555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0173-y
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