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CRISPR RNA-guided autonomous delivery of Cas9

Cas9 is an endonuclease that can be programed to autonomously deliver diverse effectors to specified genetic addresses. High-resolution structures of this protein and its associated CRISPR RNA (crRNA) guide explain the molecular mechanisms of crRNA-guided DNA recognition and provide a molecular blue...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Struct Mol Biol
Prif Awduron: Wilkinson, Royce A., Martin, Coleman, Wiedenheft, Blake
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703833/
https://ncbi.nlm.nih.gov/pubmed/30598555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0173-y
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