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PRODIGY: personalized prioritization of driver genes

MOTIVATION: Evolution of cancer is driven by few somatic mutations that disrupt cellular processes, causing abnormal proliferation and tumor development, whereas most somatic mutations have no impact on progression. Distinguishing those mutated genes that drive tumorigenesis in a patient is a primar...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioinformatics
Prif Awduron: Dinstag, Gal, Shamir, Ron
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703777/
https://ncbi.nlm.nih.gov/pubmed/31681944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz815
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