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PRODIGY: personalized prioritization of driver genes

MOTIVATION: Evolution of cancer is driven by few somatic mutations that disrupt cellular processes, causing abnormal proliferation and tumor development, whereas most somatic mutations have no impact on progression. Distinguishing those mutated genes that drive tumorigenesis in a patient is a primar...

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書目詳細資料
發表在:Bioinformatics
Main Authors: Dinstag, Gal, Shamir, Ron
格式: Artigo
語言:Inglês
出版: Oxford University Press 2020
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703777/
https://ncbi.nlm.nih.gov/pubmed/31681944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz815
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