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PRODIGY: personalized prioritization of driver genes

MOTIVATION: Evolution of cancer is driven by few somatic mutations that disrupt cellular processes, causing abnormal proliferation and tumor development, whereas most somatic mutations have no impact on progression. Distinguishing those mutated genes that drive tumorigenesis in a patient is a primar...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Dinstag, Gal, Shamir, Ron
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703777/
https://ncbi.nlm.nih.gov/pubmed/31681944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz815
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