Evidence for Many Unique Solution Structures for Chymotrypsin Inhibitor 2: A Thermodynamic Perspective Derived from vT-ESI-IMS-MS Measurements

Chymotrypsin inhibitor 2 (CI-2) is a classic model for two-state cooperative protein folding and is one of the most extensively studied systems. Alan Fersht, a pioneer in the field of structural biology, has studied the wild-type (wt) and over 100 mutant forms of CI-2 with traditional analytical and...

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Publicat a:J Am Chem Soc
Autors principals: Raab, Shannon A., El-Baba, Tarick J., Woodall, Daniel W., Liu, Wen, Liu, Yang, Baird, Zane, Hales, David A., Laganowsky, Arthur, Russell, David H., Clemmer, David E.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7702223/
https://ncbi.nlm.nih.gov/pubmed/32866376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c05365
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